HUBUNGAN KADAR KREATININ DAN ASAM URAT PADA PASIEN DIABETES MELITUS (DM) TIPE 2 DI RUMAH SAKIT UMUM BETHESDA SERUKAM

Diabetes mellitus (DM) is a chronic metabolic disease that may lead to various complications, including diabetic nephropathy, which is characterized by impaired kidney function. This study aimed to determine the relationship between serum creatinine and uric acid levels in patients with Type 2 Diabetes Mellitus at Bethesda Serukam General Hospital. This analytical observational study used a cross-sectional design. The study included 56 patients with Type 2 Diabetes Mellitus who met the inclusion criteria. The normality test showed that the data were not normally distributed; therefore, the relationship between variables was analyzed using the Spearman Rank Correlation test. The mean serum creatinine level was 1.15 ± 0.95 mg/dL, while the mean serum uric acid level was 6.50 ± 3.07 mg/dL. Most respondents (67.9%) had normal serum creatinine levels, whereas 32.1% had abnormal levels. Serum uric acid levels were equally distributed, with 50.0% of respondents classified as normal and 50.0% as abnormal. The Spearman Rank Correlation test revealed a correlation coefficient (r) of 0.487 with a p-value 0.001, indicating a statistically significant positive correlation of moderate strength between serum creatinine and serum uric acid levels. In conclusion, there is a significant positive relationship between serum creatinine and serum uric acid levels in patients with Type 2 Diabetes Mellitus at Bethesda Serukam General Hospital.