UJI ANTHELMINTIK EKSTRAK ETANOL DAUN PARE (Momordica charantia L.) TERHADAP CACING GELANG (Ascaridia galli)

Background: Ascaridia galli is a parasitic roundworm in chickens that can reduce productivity and cause mortality in severe infections. Long-term use of synthetic anthelmintics poses risks of resistance and chemical residues, prompting the need for safer herbal alternatives. Method: This research uses an experimental research type, namely a type of research that involves concentrating on independent variables to measure their effects on dependent variables, with the aim of determining the causal relationship between these variables. Purpose: This study aimed to evaluate the in vitro anthelmintic activity of ethanol extract of bitter melon (Momordica charantia L.) leaves against Ascaria galli. Treatments included three concentrations (20%, 40%, and 60%) along with positive and negative controls. Result: Results showed increasing worm mortality over time and with higher concentrations. The 60% extract achieved full mortality by the third hour, comparable to the positive control. Kruskal-Wallis and Mann-Whitney tests indicated significant differences among groups (p < 0.05). Conclusion: In conclusion, ethanol extract of bitter melon leaves has promising potential as an effective herbal anthelmintic for controlling Ascaria galli infections.